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  • An Abundant Class of Non-coding DNA Can Prevent Stochastic Gene Silencing in the C. elegans Germline

Frøkjær-Jensen C, Jain N, Hansen L, Davis MW, Li Y, Zhao D, Rebora K, Millet JR, Liu X, Kim SK, Dupuy D, Jorgensen EM, Fire AZ.

Cell (2016) June. pubmed . Publisher full access link (free access until Sep 2, 2016)

  • Random and targeted transgene insertion in C. elegans using a modified Mos1 transposon.

Frøkjær-Jensen C, Davis MW, Sarov M, Taylor J, Flibotte S, LaBella M, Pozniakovski A, Moerman DG and Jorgensen EM.

Nature Methods (2014) May 11(5), 529–534 pdf  Supplemental

  • Improved Mos1-mediated transgenesis in C. elegans.

Frøkjær-Jensen C, M Wayne Davis, Ailion M and Jorgensen EM.

Nature Methods (2012) Jan 30;9(2):117-8.   pubmed    pdf

  • The a1 subunit EGL-19, the a2/d subunit UNC-36 and the b subunit CCB-1 underlie voltage-dependent calcium currents in C.elegans striated muscle.

Lainé V#Frøkjær-Jensen C#, Couchoux H and Jospin M.

Journal of Chemical Biology (2011). Oct 21;286(42):36180-7.  #Co-first authors.    pubmed   pdf

  • MosSCI and gateway compatible plasmid toolkit for constitutive and inducible expression of transgenes in the C. elegans germline.

Zeiser E, Frøkjær-Jensen C, Jorgensen E, Ahringer J.

PLoS One (2011);6(5):e20082.  pubmed  pdf

  • Targeted gene deletions in C. elegans using transposon excision.

Frøkjær-Jensen C, Davis MW, Hollopeter G, Taylor J, Harris TW, Nix P, Lofgren R, Prestgard-Duke M, Bastiani M, Moerman DG, Jorgensen EM.

Nature Methods (2010) Jun;7(6):451-3.   pubmed     pdf

  • Single-copy insertion of transgenes in Caenorhabditis elegans.

Frøkjær-Jensen C, Davis MW, Hopkins CE, Newman BJ, Thummel JM, Olesen SP, Grunnet M, Jorgensen EM.

Nature Genetics (2008) Nov;40(11):1375-83.   pubmed     pdf

  • Ammonium-acetate is sensed by gustatory and olfactory neurons in Caenorhabditis elegans.

Frøkjær-Jensen C, Ailion M, Lockery SR.

PLoS One (2008) Jun 18;3(6):e2467.   pubmed     pdf

  • Requirement of subunit co-assembly and ankyrin-G for M-channel localization at the axon initial segment.

Rasmussen HB, Frøkjær-Jensen C, Jensen CS, Jensen HS, Jørgensen NK, Misonou H, Trimmer JS, Olesen SP, Schmitt N.

Journal of Cell Science (2007) Mar 15;120(Pt 6):953-63.   pubmed     pdf

  • Effects of voltage-gated calcium channel subunit genes on calcium influx in cultured C. elegans mechanosensory neurons.

Frøkjær-Jensen C, Kindt KS, Kerr RA, Suzuki H, Melnik-Martinez K, Gerstbreih B, Driscol M, Schafer WR.

Journal of Neurobiology (2006) Sep 1;66(10):1125-39.  pubmed     pdf

  • Searching for neuronal left/right asymmetry: genomewide analysis of nematode receptor-type guanylyl cyclases.

Ortiz CO, Etchberger JF, Posy SL, Frøkjær-Jensen C, Lockery S, Honig B, Hobert O.

Genetics (2006) May;173(1):131-49.   pubmed     pdf

  • The neurotoxic MEC-4(d) DEG/ENaC sodium channel conducts calcium: implications for necrosis initiation.

Bianchi L, Gerstbrein B, Frøkjær-Jensen C, Royal DC, Mukherjee G, Royal MA, Xue J, Schafer WR, Driscoll M.

Nature Neuroscience (2004) Dec;7(12):1337-44. Epub 2004 Nov 7.   pubmed     pdf

  • MicroRNAs act sequentially and asymmetrically to control chemosensory laterality in the nematode.

Chang S, Johnston RJ Jr, Frøkjær-Jensen C, Lockery S, Hobert O.

Nature (2004) Aug 12;430(7001):785-9.   pubmed     pdf

  •  In vivo imaging of C. elegans mechanosensory neurons demonstrates a specific role for the MEC-4 channel in the process of gentle touch sensation.

Suzuki H, Kerr R, Bianchi L, Frøkjær-Jensen C, Slone D, Xue J, Gerstbrein B, Driscoll M, Schafer WR.

Neuron (2003) Sep 11;39(6):1005-17.   pubmed     pdf

  • Pharmacological modulation of SK3 channels.

Grunnet M, Jespersen T,  Angelo K, Frøkjær-Jensen C, Klærke DA, Olesen SP, Jensen BS.

Neuropharmacology (2001). Jun 40(7):879-87.    pubmed     pdf


  • Transposon-Assisted Genetic Engineering with Mos1-Mediated Single-Copy Insertion (MosSCI).

Frøkjær-Jensen C.

Methods Mol Biol. (2015) 1327:49-58.

  • Exciting prospects for precise engineering of Caenorhabditis elegans genomes with CRISPR/Cas9.

Frøkjær-Jensen C.

Genetics (2013). Nov;195(3):635-42.          pubmed      pdf

  • Calcium: an insignificant thing. 

Frøkjær-Jensen C, Jorgensen EM.

Nature Neuroscience (2009) Oct;12(10):1213-4.          pubmed      pdf